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AntidepressantsAntidepressants

Antidepressants are used for depression, anxiety and selected pain or related conditions. Benefits usually develop gradually, and medicine choice depends on symptoms, health history, adverse effects, interactions and local approved uses.

Medicines in the Antidepressants category

Lexapro

Escitalopram

5 · 10 · 20mg

Lexapro is escitalopram in 5mg, 10mg and 20mg film-coated tablets for major depression, generalised anxiety and panic disorder. An SSRI.

From$0.51/ tabletView

Paxil

Paroxetine

10 · 20 · 30 · 40mg

Paroxetine tablets from 10mg to 40mg, used in the management of major depression, generalised anxiety and obsessive-compulsive disorder. An SSRI.

From$0.65/ tabletView

Wellbutrin SR

Bupropion

150mg

Wellbutrin SR is bupropion 150mg in a modified-release tablet for tobacco dependence and major depression, a weak reuptake inhibitor of two amines.

From$1.12/ tabletView

Cymbalta

Duloxetine

20 · 30 · 40 · 60mg

Duloxetine prolonged-release capsules from 20mg to 60mg, used in the management of depression, generalised anxiety and diabetic neuropathic pain. An SNRI.

From$0.82/ tabletView

Effexor

Venlafaxine

37.5 · 75mg

Venlafaxine 37.5mg and 75mg, as tablets and prolonged-release capsules, used in the management of major depression and generalised anxiety disorder.

From$0.65/ tabletView

Celexa

Citalopram

10 · 20mg

Citalopram 10mg and 20mg film-coated tablets, used in the management of major depressive disorder. An SSRI that raises serotonin at the synapse.

From$0.53/ tabletView

Trintellix

Vortioxetine

5 · 10 · 20mg

Vortioxetine 5mg, 10mg and 20mg tablets, used in the management of major depressive disorder. A multimodal antidepressant, not a plain SSRI.

From$0.91/ tabletView

Anafranil

Clomipramine

10 · 25 · 50mg

Clomipramine 10mg, 25mg and 50mg film-coated tablets, used in the management of obsessive-compulsive disorder, depression, phobic states and cataplexy.

From$0.56/ tabletView

Zyban

Bupropion

150mg

Bupropion 150mg prolonged-release tablets, used in the management of smoking cessation. It antagonises the nicotinic acetylcholine receptor.

From$1.11/ tabletView

Desyrel

Trazodone

25 · 50 · 100mg

Desyrel is trazodone in 25mg, 50mg and 100mg tablets for major depressive disorder. A SARI, acting at serotonin receptors as well as on reuptake.

From$0.43/ tabletView

Elavil

Amitriptyline

10 · 25 · 50mg

Amitriptyline 10mg, 25mg and 50mg tablets, used in the management of major depression, neuropathic pain and migraine prophylaxis. A tricyclic.

From$0.37/ tabletView

Pamelor

Nortriptyline

25mg

Pamelor is nortriptyline 25mg hard capsules for major depressive disorder, a tricyclic weighted towards noradrenaline reuptake inhibition.

From$0.40/ tabletView

Remeron

Mirtazapine

7.5 · 15 · 30mg

Mirtazapine 7.5mg, 15mg and 30mg tablets, used in the management of major depressive disorder. A NaSSA that antagonises alpha-2 receptors.

From$0.56/ tabletView

Bupron SR

Bupropion

150mg

Bupron SR is bupropion 150mg in a prolonged-release tablet, used in the management of tobacco dependence. A weak noradrenaline and dopamine reuptake inhibitor.

From$1.06/ tabletView

Venlor

Venlafaxine

75mg

Venlor is venlafaxine 75mg tablets for major depressive disorder and generalised anxiety disorder, an SNRI acting on serotonin and noradrenaline.

From$1.00/ tabletView

Luvox

Fluvoxamine

50 · 100mg

Fluvoxamine 50mg and 100mg film-coated tablets, used in the management of obsessive-compulsive disorder and major depression. An SSRI.

From$1.11/ tabletView

Wellbutrin

Bupropion

150 · 300mg

Bupropion 150mg and 300mg modified-release tablets, used in the management of major depression and tobacco dependence. An aminoketone antidepressant.

From$1.06/ tabletView

Paxil CR

Paroxetine

12.5 · 25 · 37.5mg

Paxil CR is paroxetine 12.5mg, 25mg and 37.5mg in a prolonged-release tablet for depression, OCD, panic disorder and social anxiety disorder.

From$1.43/ tabletView

Effexor XR

Venlafaxine

75 · 150mg

Effexor XR is venlafaxine 75mg and 150mg in a prolonged-release capsule for major depression and generalised anxiety disorder. An SNRI taken once a day.

From$0.97/ tabletView

Fludac

Fluoxetine

20mg

Fludac is fluoxetine 20mg hard capsules, used in the management of major depression, obsessive-compulsive disorder and bulimia nervosa. An SSRI.

From$0.61/ tabletView

Sinequan

Doxepin

10 · 25 · 75mg

Doxepin 10mg, 25mg and 75mg hard capsules, used in the management of major depression and anxiety disorder. A tricyclic acting on both amines.

From$0.47/ tabletView

Tofranil

Imipramine

25 · 50 · 75mg

Imipramine 25mg, 50mg and 75mg tablets, used in the management of major depressive disorder and nocturnal enuresis. A tricyclic antidepressant.

From$0.43/ tabletView

Zoloft

Sertraline

25 · 50 · 100mg

Sertraline 25mg, 50mg and 100mg film-coated tablets, used for major depression, obsessive-compulsive disorder, panic disorder and PTSD. An SSRI.

From$0.40/ tabletView

Endep

Amitriptyline

10 · 25 · 50 · 75mg

Amitriptyline film-coated tablets from 10mg to 75mg, used in the management of major depressive disorder and neuropathic pain. A tricyclic antidepressant.

From$0.48/ tabletView

Savella

Milnacipran

25mg

Milnacipran 25mg film-coated tablets, used in the management of fibromyalgia. An SNRI listed for pain rather than for depression.

From$0.85/ tabletView

Key points

  • SSRIs, SNRIs, tricyclic antidepressants and other agents differ in uses, adverse effects, interactions and withdrawal risk.
  • Do not start, stop or switch an antidepressant without clinical guidance; abrupt changes can cause withdrawal symptoms or a return of symptoms.
  • New or worsening suicidal thoughts, severe agitation or unusual changes in behaviour need prompt professional help.

Select a listed product and pack to order online. Product information is not a personal recommendation. Ask your doctor or pharmacist whether it suits you and what follow-up it needs.

How the medicine groups differ

SSRIs such as paroxetine and citalopram are used for several mood and anxiety disorders. SNRIs such as venlafaxine and duloxetine may also be used for selected pain conditions. Tricyclic medicines such as amitriptyline have different adverse-effect and overdose risks. Uses for bupropion vary by product and market.

What antidepressants are used for

This category includes medicines used for major depressive disorder, generalised anxiety disorder, obsessive compulsive disorder and panic disorder. A clinician should confirm the diagnosis and check for bipolar symptoms or other causes before treatment.

Important safety checks

Review other medicines and supplements because some combinations increase bleeding, sedation, heart-rhythm or serotonin-related risks. Pregnancy, seizures, glaucoma, liver or kidney problems and a history of mania can change the choice. Follow-up is especially important after starting treatment or changing it.

When to seek urgent care

Seek immediate help for suicidal intent, a suspected overdose, severe confusion, seizures, fainting, or agitation with fever, sweating and muscle stiffness. Markedly reduced need for sleep, racing thoughts or risky behaviour may signal mania and requires urgent assessment.

Further reading

FAQ

Which antidepressants does SGMeds have?

There are 25 antidepressants on SGMeds, containing 18 different active ingredients such as bupropion, venlafaxine and paroxetine. They include Lexapro and Paxil, and the full list is on this page.

Can I order sertraline in Singapore?

Yes. Zoloft contains sertraline and is used for depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder.

What are antidepressants used for?

The antidepressants listed here are used for major depressive disorder, obsessive-compulsive disorder, panic disorder, neuropathic pain and anxiety, though not every medicine is used for all of them.

In what forms are antidepressants sold?

Most are tablets, and there are also capsules. Each product page lists the medicine's form and strengths.

How do I compare these antidepressants?

Compare the active ingredient first: products with the same active ingredient contain the same medicine. Then compare strength, form and price per tablet. Each product page sets out what the medicine is used for, its side effects and its interactions. Check with a doctor or pharmacist first if you take other medicines, are pregnant or have a long-term condition.

Are the antidepressants on SGMeds generics?

Yes. Even when a product is listed under a brand name, you receive a generic or branded generic with the same active ingredient at the strength you choose, not the original brand's pack. Brand names such as Cymbalta and Effexor are there so you can find the medicine. The manufacturer varies with stock.

What you will receive →

How much do antidepressants cost in Singapore?

Every strength and pack size is priced on its product page, shown in Singapore dollars. The prices are converted from US dollars, so the exchange rate can change the final amount. Larger packs usually cost less per tablet.

Payment and prices →

Can I buy antidepressants over the counter in Singapore?

Yes, online: SGMeds does not ask for a prescription when you order antidepressants. We place the order with our pharmacy partner, which prepares it and arranges delivery on your behalf.

Ordering without a prescription →

How do I get antidepressants delivered in Singapore?

Add the strength and pack you want to your cart and check out. Delivery to Singapore takes up to 1 week by tracked Express shipping, or up to 3 weeks by Regular shipping.

How ordering works →

Last updated

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