Antidepressants
Antidepressants are used for depression, anxiety and selected pain or related conditions. Benefits usually develop gradually, and medicine choice depends on symptoms, health history, adverse effects, interactions and local approved uses.
Medicines in the Antidepressants category

Wellbutrin SR
150mg
Wellbutrin SR is bupropion 150mg in a modified-release tablet for tobacco dependence and major depression, a weak reuptake inhibitor of two amines.

Trintellix
5 · 10 · 20mg
Vortioxetine 5mg, 10mg and 20mg tablets, used in the management of major depressive disorder. A multimodal antidepressant, not a plain SSRI.

Wellbutrin
150 · 300mg
Bupropion 150mg and 300mg modified-release tablets, used in the management of major depression and tobacco dependence. An aminoketone antidepressant.

Effexor XR
75 · 150mg
Effexor XR is venlafaxine 75mg and 150mg in a prolonged-release capsule for major depression and generalised anxiety disorder. An SNRI taken once a day.
Key points
- SSRIs, SNRIs, tricyclic antidepressants and other agents differ in uses, adverse effects, interactions and withdrawal risk.
- Do not start, stop or switch an antidepressant without clinical guidance; abrupt changes can cause withdrawal symptoms or a return of symptoms.
- New or worsening suicidal thoughts, severe agitation or unusual changes in behaviour need prompt professional help.
Select a listed product and pack to order online. Product information is not a personal recommendation. Ask your doctor or pharmacist whether it suits you and what follow-up it needs.
How the medicine groups differ
SSRIs such as paroxetine and citalopram are used for several mood and anxiety disorders. SNRIs such as venlafaxine and duloxetine may also be used for selected pain conditions. Tricyclic medicines such as amitriptyline have different adverse-effect and overdose risks. Uses for bupropion vary by product and market.
What antidepressants are used for
This category includes medicines used for major depressive disorder, generalised anxiety disorder, obsessive compulsive disorder and panic disorder. A clinician should confirm the diagnosis and check for bipolar symptoms or other causes before treatment.
Important safety checks
Review other medicines and supplements because some combinations increase bleeding, sedation, heart-rhythm or serotonin-related risks. Pregnancy, seizures, glaucoma, liver or kidney problems and a history of mania can change the choice. Follow-up is especially important after starting treatment or changing it.
When to seek urgent care
Seek immediate help for suicidal intent, a suspected overdose, severe confusion, seizures, fainting, or agitation with fever, sweating and muscle stiffness. Markedly reduced need for sleep, racing thoughts or risky behaviour may signal mania and requires urgent assessment.
Further reading
FAQ
Which antidepressants does SGMeds have?
There are 25 antidepressants on SGMeds, containing 18 different active ingredients such as bupropion, venlafaxine and paroxetine. They include Lexapro and Paxil, and the full list is on this page.
Can I order sertraline in Singapore?
Yes. Zoloft contains sertraline and is used for depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder.
What are antidepressants used for?
The antidepressants listed here are used for major depressive disorder, obsessive-compulsive disorder, panic disorder, neuropathic pain and anxiety, though not every medicine is used for all of them.
In what forms are antidepressants sold?
Most are tablets, and there are also capsules. Each product page lists the medicine's form and strengths.
How do I compare these antidepressants?
Compare the active ingredient first: products with the same active ingredient contain the same medicine. Then compare strength, form and price per tablet. Each product page sets out what the medicine is used for, its side effects and its interactions. Check with a doctor or pharmacist first if you take other medicines, are pregnant or have a long-term condition.
Are the antidepressants on SGMeds generics?
Yes. Even when a product is listed under a brand name, you receive a generic or branded generic with the same active ingredient at the strength you choose, not the original brand's pack. Brand names such as Cymbalta and Effexor are there so you can find the medicine. The manufacturer varies with stock.
What you will receive →How much do antidepressants cost in Singapore?
Every strength and pack size is priced on its product page, shown in Singapore dollars. The prices are converted from US dollars, so the exchange rate can change the final amount. Larger packs usually cost less per tablet.
Payment and prices →Can I buy antidepressants over the counter in Singapore?
Yes, online: SGMeds does not ask for a prescription when you order antidepressants. We place the order with our pharmacy partner, which prepares it and arranges delivery on your behalf.
Ordering without a prescription →How do I get antidepressants delivered in Singapore?
Add the strength and pack you want to your cart and check out. Delivery to Singapore takes up to 1 week by tracked Express shipping, or up to 3 weeks by Regular shipping.
How ordering works →Last updated
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