Autoimmune Support
These medicines reduce or modify immune activity in autoimmune disease and transplant care. Treatment is condition-specific and usually requires specialist oversight, laboratory monitoring and infection precautions.
Medicines in the Autoimmune Support category

Methotrexate Tablets
2.5mg
Methotrexate 2.5mg tablets, used in the management of rheumatoid arthritis, psoriasis and Crohn's disease. A folic acid antagonist blocking dihydrofolate reductase.
Key points
- Immunosuppressants and disease-modifying antirheumatic drugs differ in onset, monitoring, pregnancy risks and effects on infection defence.
- Blood counts and liver, kidney or medicine-level tests may be needed before and during treatment.
- Do not stop a transplant or autoimmune medicine without the treating team, because disease flare or transplant rejection can be serious.
Select a listed product and pack to order online. Product information is not a treatment recommendation. Whether it suits you depends on specialist review and monitoring; ask your doctor or pharmacist.
How the medicine groups differ
Tacrolimus and ciclosporin require careful interaction and, in many cases, blood-level monitoring. Azathioprine, methotrexate, leflunomide and mycophenolate mofetil have different organ, blood-count and reproductive risks. A medicine may have roles in more than one condition, but its monitoring plan is not transferable.
What these medicines are used for
This category includes medicines used for rheumatoid arthritis, systemic lupus erythematosus, psoriasis and prevention or treatment of transplant rejection. What they share is a damping effect on immune activity, but they differ widely in how selective that effect is, so one is rarely interchangeable with another. The diagnosis, not the category, decides which is appropriate.
Important safety checks
Tell the treating team about infection symptoms, vaccination plans, pregnancy or pregnancy planning, and every medicine or supplement. Live vaccines may be unsuitable during some treatments. Avoid changing brands, formulations or timing of transplant medicines without specialist and pharmacy confirmation.
When to seek urgent care
Seek prompt medical care for fever, breathing difficulty, a painful spreading rash, unusual bruising or bleeding, severe mouth ulcers, jaundice or markedly reduced urine. Transplant recipients should urgently contact their team for missed doses, persistent vomiting or possible rejection symptoms.
Further reading
FAQ
Which autoimmune medicines can I order on SGMeds?
There are 11 autoimmune medicines on SGMeds, containing 9 different active ingredients such as tacrolimus, an immune-suppressing medicine (ciclosporin) and hydroxychloroquine. They include Plaquenil and Methotrexate Tablets, and the full list is on this page.
Which medicines are used for lupus?
Medicines for lupus on SGMeds include Plaquenil (hydroxychloroquine) and Imuran (azathioprine).
Which conditions are these autoimmune medicines for?
The autoimmune medicines listed here are used for rheumatoid arthritis, transplant rejection, systemic lupus erythematosus, psoriasis and atopic dermatitis, though not every medicine is used for all of them.
In what forms are autoimmune medicines sold?
Most are tablets, and there are also capsules and ointments. Each product page lists the medicine's form and strengths.
How do I choose between the autoimmune medicines on SGMeds?
Compare the active ingredient first: products with the same active ingredient contain the same medicine. Then compare strength, form and price per unit. Each product page sets out what the medicine is used for, its side effects and its interactions. Check with a doctor or pharmacist first if you take other medicines, are pregnant or have a long-term condition.
Do I get brand-name or generic autoimmune medicines?
Generics. Even when a product is listed under a brand name, you receive a generic or branded generic with the same active ingredient at the strength you choose, not the original brand's pack. Brand names such as Olumiant and Arava are there so you can find the medicine. The manufacturer varies with stock.
What you will receive →How much do autoimmune medicines cost in Singapore?
Every strength and pack size is priced on its product page, shown in Singapore dollars. The prices are converted from US dollars, so the exchange rate can change the final amount. Larger packs usually cost less per unit.
Payment and prices →Can I buy autoimmune medicines over the counter in Singapore?
Yes, online: SGMeds does not ask for a prescription when you order autoimmune medicines. We place the order with our pharmacy partner, which prepares it and arranges delivery on your behalf.
Ordering without a prescription →Where can I buy autoimmune medicines online in Singapore?
You can order them here on SGMeds. Pick the product, strength and pack, add it to your cart and check out. We deliver to Singapore and Malaysia: Express shipping is tracked and takes up to 1 week, Regular shipping up to 3 weeks.
How ordering works →Last updated
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