Buspirone
Buspirone is an anxiolytic used regularly for selected anxiety disorders. It does not provide immediate relief during a panic attack and its benefit develops over time. Listed uses include generalised anxiety disorder.
Key points
- Buspirone is taken as a planned ongoing treatment rather than only when anxiety peaks.
- Serotonergic medicines, monoamine-oxidase inhibitors, grapefruit and liver or kidney problems require review.
- Suicidal intent, severe agitation with fever or muscle rigidity, or a serious allergic reaction needs urgent care.
Listings are for comparison only. Suitability and supply depend on clinician and pharmacy checks, stock, destination rules and prescription requirements.
How it works
Buspirone acts mainly as a partial agonist at serotonin 5-HT1A receptors and also affects dopamine signalling. It is not a benzodiazepine and has a different onset and withdrawal profile.
Important safety checks
Liver or kidney impairment, pregnancy, recent monoamine-oxidase-inhibitor use and other serotonergic medicines require review. Alcohol and sedating medicines can worsen dizziness. Follow product instructions about grapefruit and avoid driving until individual effects are known.
When to seek urgent care
Seek urgent help for suicidal intent, severe agitation or confusion with sweating, fever, diarrhoea, tremor or muscle rigidity, fainting, facial swelling or breathing difficulty.