A-Ret
A-Ret is topical tretinoin at 0.1%, supplied as a cream and a gel and used for acne vulgaris. The retinoid raises turnover of follicular skin cells.
- Condition
- Acne Vulgaris
- Alternative names
- Obagi Tretinoin; Retrieve Cream; Retino-A; Tretinoin
- Therapeutic class
- Retinoid
- Pharmacological class
- Retinoid
- Known off-label uses
- photoaging
- Contraindications
- hypersensitivity to tretinoin; pregnancy; known history of epithelioma
- Minor side effects
- erythema; dry skin; peeling; pruritus
- Moderate side effects
- photosensitivity
- Serious side effects
- severe skin irritation, requires immediate medical attention
- Dosage forms
- Cream; Gel
- Administration route
- Cutaneous use
- Manufacturer
- iNova Pharmaceuticals
- Onset time
- 2–4 weeks
- Duration
- 12–24 weeks
- Storage instructions
- Store at controlled room temperature, away from direct sunlight.
- Drug interactions
- benzoyl peroxide; salicylic acid
- Age restrictions
- Use with caution in adolescents.
Precautions and warnings
avoid sun exposure; avoid contact with mucous membranes; use non-comedogenic cosmetics
Patient summary
A-Ret is topical tretinoin at 0.1%, supplied as a cream and a gel and used for acne vulgaris. The retinoid raises turnover of follicular skin cells.
Mechanism of action
Tretinoin is a vitamin A derivative that increases the turnover of follicular epithelial cells, preventing the formation of microcomedones and promoting the expulsion of existing comedones.
Pregnancy and breastfeeding
Pregnancy: Contraindicated due to risk of teratogenicity. Breastfeeding: Not recommended.
A-Ret contains tretinoin, an active ingredient for treating Acne Vulgaris. The same compound is also sold under names such as Obagi Tretinoin, Retrieve Cream, Retino-a, and Tretinoin. Manufactured by iNova Pharmaceuticals, this product is available in a 0.1% strength, supplied in a tube.
Buying A-Ret online
Generic tretinoin is often more affordable than original brand equivalents, improving access for expats and those living in areas where finding consistent supply at local retailers is difficult.